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Chapter: 6 / Q: 16
A 65 year old man presents with back pain. Exam: splenomegaly and anemia. Blood: WBC 22, Hgb 10.9, Plt 100, ESR 25. He has been found to have Philadelphia chromosome. What is the single most likely diagnosis?
Chapter: 6 / Q: 17
A 15 year old girl was admitted with anemia, chest infection and thrombocytopenia. She was treated and her symptoms had regressed. She was brought again with fever and the same symptoms a few days later. She also seems to have features of meningitis. What is the most likely diagnosis?
Chapter: 6 / Q: 18
A 5 year old boy has cough and swelling at the knee after falling on the ground with rashes on the buttocks which are non-blanching. PT 13, APTT 71, Hgb 11, WBC 8, Plt 200. Choose the most likely diagnosis?
Chapter: 6 / Q: 19
A 40 year old lady who has been a smoker since she was a teenager has the following blood result: Hb 19. What hormone should you check?
Chapter: 6 / Q: 20
A 55yo man presents with HTN. He complains of headache and visual disturbances. He also reports itching after a hot bath and burning sensation in finger and toes. His face is flushed red. PE: mild splenomegaly. Inv: Hgb=20g/dl, WBC=20, plt=500, EPO normal. What is the likely dx?
Chapter: 6 / Q: 21
A 12 year old boy complains of acute development of purpura on the dependent areas of his body 2weeks after a URTI. The purpura doesn’t blanch on pressure, tests reveal: Hb 12, platelets 50, WBC 5, Bleeding time 10mins, APTT 40seconds, PT 1.02. What is the most likely dx?
Chapter: 6 / Q: 22
A young man who has no past medical history presented with jaundice, low Hgb, reticulocytes 8% and other indices within normal limit but occasional spherocytes were seen on blood film. What is the single most appropriate investigation?
Chapter: 6 / Q: 23
A 55 year old male after gastrectomy developed anemia. His MCV=106fl. Exam: loss of proprioception and vibration sense. What is the most likely diagnosis?
Chapter: 6 / Q: 24
A 4 year old boy presents with recurrent episodes of self limiting spontaneous bleeding. Coagulation test: PT normal, bleeding time normal, APTT prolonged, Factor VIII decreased. His father and uncle suffer from a similar illness. What is the most likely dx?
Chapter: 6 / Q: 25
A young boy has a history of epistaxis. CBC normal, except APTT 47s. What is the most likely diagnosis?
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