A 65 year old man presents with back pain. Exam: splenomegaly and anemia. Blood: WBC 22, Hgb 10.9, Plt 100, ESR 25. He has been found to have Philadelphia chromosome. What is the single most likely diagnosis?
belongs to book: 1700 MCQ REVISED VERSION TOPIC WISE|DR. KHALID SAIFULLAH|4th EDITION| Chapter number:6| Question number:16
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Medicine
The key is C. CML. [anaemia, raised WBC count, low platelet (platelet may be variable) are known features of CML, splenomegaly (particularly if massive) is very suggestive of CML and Philadelphia chromosome is characteristic of CML].
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