Q:

A 55 year old male after gastrectomy developed anemia. His MCV=106fl. Exam: loss of proprioception and vibration sense. What is the most likely diagnosis?

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A 55 year old male after gastrectomy developed anemia. His MCV=106fl. Exam: loss of proprioception and vibration sense. What is the most likely diagnosis? 


  1. IDA (iron deficiency anemia)
  2. Folate def
  3. Vit B12 def
  4. Anemia of chronic disease

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The key is C. Vit B12 def. [gastrectomy –> deficiency of intrinsic factor –> Vitamin B12 def. leading to macrocytic anemia and resulting subacute combined degeneration of cord causing loss of proprioception and loss of vibration sense]. 

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