For each of the lesions on the left select the most appropriate association from the list on the right

The answer is E, A, B. In visceral leishmaniasis ('Kala-azar') the organisms infect macrophages.

In African trypanosomiasis the flagellates stay in the circulation, enter the central nervous system and alter the sleep rhythm.

In cutaneous leishmaniasis a papule develops at the site of the insect bite and ulcerates.

In mucocutaneous leishmaniasis (C) non-healing secondary ulcers occur months or years after the primary lesion. South American trypanosomiasis (D) is characterised by infection of organs by the parasite (Chagas' disease); the loss of bowel ganglion cells is a notable feature.