Q:

For each effect on the left select the most appropriate pituitary lesion from the list on the right

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For each effect on the left select the most appropriate pituitary lesion from the list on the right.

a. Acromegaly.

b. Cushing's syndrome.

c. Sheehan's syndrome.


  1. Craniopharyngioma.
  2. Auto-immune disease.
  3. Hyaline-change in pituitary basophils.
  4. Post partum necrosis.
  5. Rathke\'s cyst.

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The answer is B, C, D. Eosinophil-cell adenomas secrete growth hormone which produce acromegaly in the adult, and result in gigantism when present before the epiphyse fuse.

Excess ACTH results in increased production of glucocorticoids by adrenals. Hyalinechange is a constant finding in the anterior pituitary.

Post partum hypotension results in ischaemic necrosis, in the enlarged pituitary of pregnancy; this results in panhypopituitarism.

Craniopharyngioma (C) and Rathke's cyst (E) are benign lesions of the suprasellar region which may result in anterior pituitary damage by pressure necrosis.

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