Q:

Rapidly progressive glomerulonephritis is best characterized morphologically by which ONE of the following?

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Rapidly progressive glomerulonephritis is best characterized morphologically by which ONE of the following?


  1. Basement membrane thickening.
  2. Crescent formation.
  3. Fibrinoid necrosis of the afferent arteriole.
  4. Interstitial fibrosis.
  5. Mesangial cell proliferation.

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The answer is B. Proliferation of the parietal epithelium of Bowman's capsule forms epithelial crescents which fill the capsular space.

Interstitial fibrosis (D) can have many causes but is seen where there is loss of glomeruli with resultant atrophy of the nephron.

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