Q:

Which ONE of the following is characteristically found in acute diffuse proliferative glomerulonephritis?

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Which ONE of the following is characteristically found in acute diffuse proliferative glomerulonephritis?


  1. Endothelial and mesangial cell hyperplasia.
  2. Fibrinoid necrosis of glomerular capillaries.
  3. Focal sclerosis of glomerular tufts.
  4. Hyalinization of arcuate arteries.
  5. Severe basement membrane thickening.

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The answer is A. The characteristic finding in this type of glomerulonephritis is enlargement and hypercellularity of the glomeruli, contributed to by capillary endothelial cell and mesangial cell hyperplasia.

Fibrinoid necrosis of glomerular capillaries (B) and hyalinization of arcuate arteries (D) are seen in malignant phase hypertension.

Focal sclerosis (C) of glomerular tufts is seen in focal glomerulosclerosis. Basement membrane thickening (E) is seen in membranous glomerulonephritis. 

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