Q:

For each of the types of virus infection listed on the left select the most appropriate association from the list on the right

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For each of the types of virus infection listed on the left select the most appropriate association from the list on the right.

a. Cytomegalovirus.

b. Herpes simples virus.

c. Type 1 poliomyelitis virus.


  1. Anterior horn motor cells.
  2. Bilateral temporal lobe necrosis.
  3. Gasserian ganglion affected.
  4. Inclusion body in Purkinje cell cytoplasm.
  5. Nuclear inclusion bodies found in periventricular cells.

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The answer is E, B, A. Cytomegalovirus infection of the CNS is usually acquired in utero and is characterized by intranuclear inclusion bodies.

Herpes simplex infection of the CNS gives bilateral temporal lobe necrosis (acute necrotizing encephalitis).

Poliomyelitis affects the motor cells of the anterior horns of the spinal cord.

The Gasserian ganglion is a common site of infection by Zoster (varicella) virus (C).

Inclusion bodies in the cytoplasm of the Purkinje cells of the cerebellum (D) is a diagnostic feature of rabies (Negri bodies).

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