Q:

For each outcome of infection by hepatitis B (HB) virus on the left select the most appropriate association from the list on the right

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For each outcome of infection by hepatitis B (HB) virus on the left select the most appropriate association from the list on the right.

a. Asymptomatic HB carrier with low infectivity.

b. HB positive chronic active hepatitis.

c. Recovery from acute hepatitis B.


  1. Anti-mitochondrial antibody develops.
  2. HBcAb and HbsAb produced.
  3. HBcAg and HbsAg both expressed in hepatocyte.
  4. Predominant HBcAg expression.
  5. Predominant HBsAg expression in serum and hepatocytes.

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The answer is E, C, B. If virus is not completely eliminated a carrier state may develop with continued expression of HBsAg; this is viral envelope and is of low infectivity.

In some cases chronic liver disease develops with continued expression of HBcAg and HBs Ag.

Successful elimination of virus with resolution of the hepatitis results from adequate humoral responses.

Antimitochondrial Ab (A) is present in primary biliary cirrhosis. Predominant HBcAg (D) expression occurs in carriers who remain highly infective.

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