Q:

For each of the types of plasma cell tumour listed on the left select the most appropriate association from the list on the right

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For each of the types of plasma cell tumour listed on the left select the most appropriate association from the list on the right.

a. Heavy chain disease.

b. Light chain myeloma.

c. Macroglobulinaemia. 


  1. Bence-Jones proteinuria.
  2. Increased blood viscosity.
  3. Increased red cell mass.
  4. Mediterranean lymphoma.
  5. Solitary tumour in a long bone.

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The answer is D, A, B. This rare condition involves a neoplastic proliferation of lymphoid cells in the mucosa of the small intestine; the cells produce alpha chain.

Bence-Jones protein consists of light chains of immunoglobulin molecules; 15 per cent of myelomas produce only light chains.

Waldenstrom's macroglobulinaema is a condition in which the neoplastic cells produce IgM which increases blood viscosity.

ncreased cell mass occurs in the myeloproliferative disorder polycythaemia rubra vera (C).

A solitary tumour in a long bone is typical of a solitary plasmacytoma (E).

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