Q:

For each of the types of acute leukaemia listed on the left select the most appropriate association from the list on the right

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For each of the types of acute leukaemia listed on the left select the most appropriate association from the list on the right.

a. Acute lymphoblastic leukaemia (L1).

b. Acute monoblastic leukaemia (M5).

c. Acute myeloblastic leukaemia (M2).


  1. Blast cells are Sudan Black positive.
  2. Leukaemic cells with cytoplasmic projections.
  3. Philadelphia chromosome positive.
  4. Sodium fluoride sensitive non-specific esterase activity.
  5. Tumour cells usually lack B- or T-cell markers.

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The answer is E, D, A. In ALL, especially in children, there are usually no B- or T-cell markers and this indicated a good response to chemotherapy.

This enzyme histochemical reaction distinguishes monoblasts from myeloblasts.

The presence of Sudan Black B or peroxidase positive granules indicated a myeloblast origin.

Leukaemic cells with cytoplasmatic projections are found in hairy cell leukaemia which is of B-cell origin (B).

Philadelphia chromosome (C) is a marker of chronic granulocytic leukaemia.

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