For each of the types of haemolytic anaemia listed on the left select the most appropriate description from the list on the right

The answer is E, C, D. Rhesus incompatibility result in maternal iso-antibody production which crosses the placenta and may cause haemolysis in the baby.

This is a genetically determined red cell membrane defect, involving the membrane protein spectrin.

Red cell fragmentation occurs in several conditions in which small vessels are crisscrossed by strands of fibrin.

Abnormal sensitivity to cold (A) is one form of autoimmune haemolytic anaemia in which the auto-antibodies react only below 37 °C, causing auto-agglutination and lysis.

Defective haemoglobin synthesis (B) results in the haemoglobinopathies.