Q:

Which ONE of the following compounds is not associated with pulmonary fibrosis/or Alveolar damage

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Which ONE of the following compounds is not associated with pulmonary fibrosis/or Alveolar damage.


  1. Asbestosis.
  2. Bleomycin.
  3. Busulphan.
  4. Paraquat.
  5. Stilboestrol.

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The answer is E. Stilboestrol is not known to cause pulmonary fibrosis. The other compounds may all cause pulmonary fibrosis; paraquat (D) taken either accidentally or intentionally causes severe intra-alveolar fibrosis; the other drugs all cause pulmonary fibrosis in a proportion of patients. Amiodarone (A) causes aggregation of macrophages in alveoli.

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