Q:

From the list of diseases on the left select the most appropriate histological description from the list on the right

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From the list of diseases on the left select the most appropriate histological description from the list on the right.

a. Infiltration of aortic adventitia with plasma cells and lymphocytes.

b. Periarteritis and endarteritis of the aortic vasa vasorum.

c. Thrombotic occlusion of short lengths of arteries and veins of limbs.


  1. Buerger\'s disease.
  2. Giant cell (temporal) arteritis.
  3. Raynaud\'s disease.
  4. Rheumatoid arteritis.
  5. Syphilitic aortitis.

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The answer is D, E, A. Lesions similar to those seen in the heart in rheumatic fever can be found in the walls of larger veins.

The arteritic lesion of syphilis involves the whole vessel wall; damage to the vasa vasorum results in damage to the aortic media with aneurysm formation; this is usually in the thoracic aorta.

Buerger's disease (thromboangiitis obliterans) involves both arteries and veins.

Giant cell (temporal) arteritis (B) occurs in the elderly; there is destruction of the elastic lamina with giant cell formation.

Raynaud's disease (C) is associated with abnormal spasm of digital vessels; the histological features are uncertain.

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