From the list of tumour types on the right select the most appropriate mode of spread from the list on the left

The answer is C, A, D. Gastric carcinoma of signet ring cell type spreads to the ovary in premenopausal women (Kruckenberg tumour).

Paget's disease of the breast is the only common example of this; malignant cells from underlying breast cancer extend upwards into the nipple skin from the nipple ducts involved by intraduct carcinoma.

Prostatic carcinoma invades the vessels of the intravertebral venous plexus in which flow is reversed into the vertebral bodies.