In which ONE of the following animal species does an experimental model for bladder carcinogenesis by 2-naphthylamine exist?
belongs to book: MCQs in Pathology|I L Brown|| Chapter number:10| Question number:48
All Answers
total answers (1)
belongs to book: MCQs in Pathology|I L Brown|| Chapter number:10| Question number:48
total answers (1)
The answer is B. Epidemiological evidence implicated 2-naphthylamine as a potential bladder carcinogen in the aniline dye industry; only dogs and man convert the noncarcinogenic 2-naphthylamine to carcinogenic 1-hydroxy-2-naphthylamine in the kidney.
This carcinogen is concentrated in the urine and can induce urothelial tumours.
need an explanation for this answer? contact us directly to get an explanation for this answer