Q:

For each of the features of the clotting (coagulation) mechanism on the left select the most appropriate association from those on the right

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For each of the features of the clotting (coagulation) mechanism on the left select the most appropriate association from those on the right.

a. Common pathway.

b. Extrinsic pathway.

c. Intrinsic pathway


  1. Can occur in the test tube.
  2. Converts prothrombin to thrombin.
  3. Produced by fibroblasts.
  4. Production of plasmin.
  5. Result of tissue injury

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The answer is B, E, A. The common pathway (produced by extrinsic or intrinsic routes) results in the conversion of prothrombin to thrombin, which converts fibrinogen to fibrin monomer.

The extrinsic pathway is the result of the action of thrombokinase produced by tissue injury.

The intrinsic pathway results in clotting without the participation of tissue injury factors.

The production of plasmin (D) is the result of the action of activators on plasminogen and is responsible for the solubilization of fibrin. Fibrin is not produced by fibroblasts (C).

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