For each of the types of immunological deficiency states listed on the left select the most appropriate association from those on the right

The answer is C, A, B. Di George syndrome - defective TT-cell function. There is almost complete failure of development of the thymus and parathyroids from the third and fourth branchial arches.

Infantile sex-linked agammaglobulinaemia - defective B-cell function. This selective B-cell defect (Bruton type) results in failure to produce IgG, IgM and IgA.

Severe combined immunodeficiency - defective B- and T-cell function. This combined type (Swiss type) of agammaglobulinaema has failure of development of both thymus dependent and thymus independent systems.

Platelets are abnormal (D) in the rare Wiskott-Aldrich syndrome in which T-cell function, IgM and IgA are also abnormal.

Abnormal vessels (E) are a feature of ataxia telangiectasia in which there is abnormal cell mediated immunity and low levels of IgA and IgE.