For each of the features of a lymph node listed on the left select the most appropriate association from those on the right?
belongs to book: MCQs in Pathology|I L Brown|| Chapter number:5| Question number:22
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belongs to book: MCQs in Pathology|I L Brown|| Chapter number:5| Question number:22
total answers (1)
The answer is C, E, D. Expansion of the deep cortex (paracortex) of the lymph node - region of T-cell response. The deep (or para) cortex is the T-lymphocytic zone of the lymph node and this enlarges during antigenic stimulus resulting in a cell mediated response.
Primary lymphoid nodules - superficial cortex of unstimulated lymph node. In the unstimulated lymph node there are localized aggregates of lymphocytes in the superficial cortex.
Production of germinal centres - superficial cortex of stimulated lymph node. Following antigenic stimulation of a type resulting in antibody production (humoral response) the primary nodules enlarge, to become germinal centres where B-lymphocytes proliferate.
During the humoral response plasma cells are produced and these may be seen in the cortex deep to the germinal centres and in the medullary cords.
Macrophages are present lining the lymph sinuses and in some forms of stimulation may become very prominent (sinus histiocytosis).
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