Q:

If the following events were placed in their most probable order of occurrence following a skin wound which would come fourth?

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If the following events were placed in their most probable order of occurrence following a skin wound which would come fourth?


  1. Blood clot formation.
  2. Growth of granulation tissue.
  3. Loss of vascularity of fibrous scar.
  4. Migration of epithelial cells from wound edges.
  5. Wound edges united by collagen.

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The answer is E. In a wound healing by first intention the gap fills with blood clot (A); epithelium migrates from the wound edges and within 48 hours the gap is bridged by epithelium (D); granulation tissue grows into the wound (B) forming a scaffolding by which the wound edges are united by collagen (D), producing a narrow fibrous scar which gradually loses its vascularity (C).

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