Q:

For each of the cell type listed on the left choose the most appropriate association from those on the right

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For each of the cell type listed on the left choose the most appropriate association from those on the right.

a. Alveolar macrophages.

b. Kupffer cells.

c. Langhans' giant cells. 


  1. CNS phagocytes.
  2. Digest bone matrix.
  3. Lining cells of hepatic sinusoids.
  4. Nuclei arranged peripherally in the cytoplasm.
  5. Phagocytic activity dependent on oxygen.

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The answer is E, C, D. Alveolar macrophages - phagocytic activity dependent on oxygen. The alveolar macrophages illustrate the point that local environment may influence cellular function; unlike other phagocytic cells these cells require high oxygen tension for full activity.

Kupffer cells - lining cells of hepatic sinusoids. The Kupffer cell lines the hepatic sinusoids and is active in phagocytosis of particulate matter in the liver.

Langhans' giant cell - nuclei arranged peripherally in the cytoplasm. The Langhans' giant cell characteristically has a large number of peripherally arranged nuclei; this cell is typical of the tuberculous granuloma.

Central nervous system phagocytes. The representative of the mononuclear phagocyte system in the CNS (A) is the microglial cell.

Digest bone matrix. Osteoclasts are derived from bone marrow precursors and digest matrix (B).

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