Which ONE of the following is not an acceptable characteristic of a granuloma

The answer is E. Composed of polymorphonuclear leucocytes, cellular debris and fibrin - This is a description of pus as would be found in an abscess. Polymorphonuclear leucocytes and nuclear debris can be found in a true granuloma if there is a focus of suppuration: an infective granuloma.

The definition of 'granuloma' is controversial; it may be used to mean a chronic inflammatory lesion forming a tissue mass or it may be restricted to a lesion composed of macrophages or even of altered macrophages (epithelioid cells).