Q:

For each of the causes of membrane damage listed on the left select the most appropriate association from those listed on the right

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For each of the causes of membrane damage listed on the left select the most appropriate association from those listed on the right.

 a. C. welchii aphlatoxin.

b. Hypoxia.

c. Ouabain.


  1. Digestive damage to cell membrane.
  2. Failure of oxidative phosphorylation in mitochondria.
  3. Mechanical rupture of cell membrane.
  4. Poisoning of cell membrane ion pump.
  5. Stimulation of cell membrane ion pump.

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The answer is A, B, D. Clostridium welchii aphlatoxin is a lecithinase which digests cell membrane resulting in increased permeability.

Hypoxia results in decreased oxidative phosphorylation in mitochondria with resultant lack of ATP.

Ouabain is a specific cell membrane ion pump antagonist which competes with K+ for a site on Na+K+ dependent ATP ase.

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