For each of the patterns of inheritance on the left select the most appropriate disease from those on the right

The answer is D, E, C. Glycogen storage disease is an autosomal recessive specific enzyme deficiency that results in excessive accumulation of glycogen in liver, kidney, myocardium.

In neurofibromatosis a dominant character is expressed in one parent and can be expected in half of the offspring; multiple tumours of small nerves are present in this condition.

Duchenne muscular dystrophy is X-linked recessive disease. The gene for this form of muscular dystrophy is present on the X chromosome, hence females are not affected (being XX) while males are (being XY).

Ankylosing spondylitis is a disease of the vertebral column which is associated with a specific HLA type.

Breast cancer may tend to recur in particular families but there is no known genetic component.