Q:

A 56-year-old male patient’s status has gotten worse over the past 2 hours. He went from an air entrainment mask to a nonrebreather, and is now receiving positive pressure ventilation with the following settings:

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A 56-year-old male patient’s status has gotten worse over the past 2 hours. He went from an air entrainment mask to a nonrebreather, and is now receiving positive pressure ventilation with the following settings:

Assist control rate of 12

Tidal volume 650 mL

FIO2 100%

PIP 40 cm H2O

Plateau pressure 35 cm H2

The patient's arterial blood gas results are:

pH 7.42

PaCO2 35 torr

PaO2 54 torr

SpO2 84%

HCO3- 23 mEq/L

Which of the following best represents the status of this patient?


  1. Cystic fibrosis
  2. Acute metabolic alkalosis
  3. Hypoventilation from fatigue
  4. A significant intrapulmonary shunt

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