The most common reason for surgical amputation in the general population is:

E. Ischemia.

DISCUSSION: Congenital deformities leading to amputation are relatively rare, as are musculoskeletal tumors. Traumatic amputations are the most common in the younger population, but the majority of amputations are of the lower extremity and are caused by ischemia secondary to peripheral vascular disease. Approximately 50% of the patients suffering from extremity ischemia also suffer from diabetes.