Which of the following syndromes are associated with the development of Wilms’ tumor?

a. Beckwith-Wiedemann Syndrome (hemi-hypertrophy, macroglossia, aniridia)

b. Neurofibromatosis

c. Denys-Drash syndrome (pseudohermaphroditism, glomerulopathy)

d. Gonadal dysgenesis

A number of syndromes are associated with the development of Wilms’ tumors and when present, require routine periodic screening. There is no known association of the hemolytic uremic syndrome with the development of Wilms’ tumor.