Which of the following statements regarding retroviruses is/are correct?
belongs to book: ASIR SURGICAL MCQs BANK|Dr. Gharama Al-Shehri|1st edition| Chapter number:15| Question number:39
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belongs to book: ASIR SURGICAL MCQs BANK|Dr. Gharama Al-Shehri|1st edition| Chapter number:15| Question number:39
total answers (1)
a. The genetic material contained within a retrovirus is RNA
c. Proviral DNA is integrated into the host chromosome
Retrovirus particles are composed of a ribonucleic acid (RNA) genome encapsidated into a complex virus particle structure containing both viral and cellular components The virus enters cells primarily on the basis of interactions between viral coat proteins and complementary proteins on the host cell membrane. Once internalized, the viral RNA is converted to a double stranded DNA sequence, the provirus. The proviral DNA is integrated into the host chromosome by means of an integrase protein utilizing proviral DNA sequences known as long terminal repeats. An important point is the need for host cell replication for successful proviral DNA integration.
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