A 42-year-old woman presents with an 8 cm. × 6 cm. × 4 cm. mass in the posterior thigh. Incisional biopsy reveals a high-grade liposarcoma. Her management should include:

C. Complete excision with negative margins.

D. Adjuvant radiation therapy.

DISCUSSION: This is a common presentation of soft tissue sarcoma. Surgery remains the principal modality for curative therapy for all soft tissue sarcomas. Provided the entire tumor is removed, less radical procedures have not been demonstrated to adversely affect local recurrence or outcome. The surgical objective is complete removal of the tumor with negative margins and maximal preservation of function. Adjuvant radiation improves local control. Adjuvant chemotherapy has not proven to be efficacious.