Q:

Which of the following are true of OKT3?

0

Which of the following are true of OKT3?


  1. It is not a monoclonal antibody.
  2. It binds to the T-cell receptor and inactivates T-cell function
  3. It is the monoclonal antibody most frequently used in clinical transplantation.

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B. It binds to the T-cell receptor and inactivates T-cell function.

C. It is the monoclonal antibody most frequently used in clinical transplantation

DISCUSSION: OKT3 is a monoclonal antibody produced in limitless supply by a hybridoma. It binds to a site associated with the T-cell receptor complex to inactivate the T cell. It is the most widely used monoclonal antibody in clinical transplantation.

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