Which of the following is/are true regarding treatment of diabetes?

c. The effects of diabetes are most marked in individuals with other risk factors

The effect of diabetes is most marked in societies and groups in which the prevalence of atherosclerosis is high even in the absence of diabetes. The impact is not uniform but rather seems to parallel the population in which the diabetic person finds himself augmenting or facilitating the effects of other risk factors. There is little evidence that oral hypoglycemic agents or insulin treatment reduces the incidence of cardiovascular sequela in diabetic persons. Further most diabetics have other appreciable risk factors for atherosclerosis and diabetic persons with optimal levels of other risk factors appear to have little excess risks.