Which of the following is/are true with respect to hypertension?

c. Common antihypertensive regimens may have adverse effects on a patient’s lipid profile

As with the other risk factors there does not appear to be a threshold effect of blood pressure on the risk of cardiovascular complications-even mild elevations convey significant risk. Morbidity of hypertension is strongly correlated with the risk of developing stroke but hypertension also causes peripheral and coronary atherosclerosis. Unfortunately both beta blockers and thiazide diuretics can adversely affect lipid profiles. Overly aggressive lowering of blood pressure in patients with ischemic heart disease has been associated with increased mortality. Nevertheless blood pressure reduction has been shown to be a significant factor in decreasing cardiovascular events in long term follow-up.