Concerning the treatment of thrombotic vascular disease, the following is/are true:

c. Ticlopidine is more effective than aspirin in patients with cerebrovascular disease

d. Ticlopidine prevents fibrinogen binding to the GPIIb-IIIa receptor complex

Aspirin and other anti-platelet drugs are effective in preventing thrombosis in arterial but not venous thrombotic disorders. Dipyridamole has been found to be ineffective in rigorous clinical trials. Ticlopidine is more effective than aspirin in patients with cerebrovascular disease, and serves to prevent fibrinogen binding to the platelet GPIIb-IIIa complex.