Q:

Concerning the inhibition of intravascular coagulation, the following is/are true:

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Concerning the inhibition of intravascular coagulation, the following is/are true:


  1. Heparin accelerates the effects of ATIII to a greater extent than native heparin sulfate
  2. Protein C but not protein S is vitamin K dependent
  3. Protein Ca stimulates the release of TAP from endothelial cells
  4. ATIII neutralizes factors Xa, IXa and IIa

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a. Heparin accelerates the effects of ATIII to a greater extent than native heparin sulfate

c. Protein Ca stimulates the release of TAP from endothelial cells

d. ATIII neutralizes factors Xa, IXa and IIa

The rate of inhibition of activated coagulation factors by ATIII is dramatically accelerated by heparin, and to a lesser extent by heparin sulfate. Both protein C and protein S are vitamin K dependent, and protein Ca does stimulate the release of TAP from endothelial cells. ATIII neutralizes factors Xa, IXa and IIa (thrombin). 

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