Q:

Which of the following statements correctly characterizes the healing of prosthetic arterial grafts in humans?

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Which of the following statements correctly characterizes the healing of prosthetic arterial grafts in humans? 


  1. Complete healing occurs within 3 months of graft implantation.
  2. Complete healing occurs within 1 year of graft implantation.
  3. Prosthetic grafts do not heal completely in humans.
  4. Polytetrafluoroethylene (PTFE) grafts heal completely whereas Dacron grafts do not.
  5. Dacron grafts heal completely but PTFE grafts do not.

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C. Prosthetic grafts do not heal completely in humans.

DISCUSSION: Prosthetic grafts of any kind do not heal completely in humans as they do in experimental animals. Some healing occurs in the perianastomotic regions, but the majority of the graft's luminal surface never develops a living neointima; rather, it remains covered with a compacted layer of fibrin. 

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