In prevention of the fat emboli syndrome the primary therapy can be accomplished by which of the following?

D. Maintaining a serum albumin value greater than 3 gm. per 100 ml. in the days immediately following injury.

DISCUSSION: The mechanism producing fat emboli syndrome is primarily release of free fatty acids that produce a change in the capillary alveolar membrane. Albumin is the primary binder of fatty acids. With serum levels greater than 3 gm. per 100 ml., 99% of the circulating free fatty acid remains in the bound configuration. Alcohol, heparinization, and steroids have been shown to have no direct effect on fat emboli syndrome, and serious side effects are related to their use.