In the medical management of coronary artery disease, the following is/are true:

b. b-blocking agents act to reduce myocardial O2 demand

c. Ca-channel blocking agents reduce ventricular contractility

Nitroglycerin primarily dilates venous capacitance vessels, but at higher doses can produce coronary and systemic arterial dilation. b-adrenergic blocking agents reduce myocardial O2 demand by decreasing heart rate and contractility. Ca-channel blocking agents reduce ventricular contractility, produce vasodilation and may protect myocytes. They are particularly effective for coronary vasospastic disease.