Q:

Which of the following statements about malignant cardiac tumors are true?

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Which of the following statements about malignant cardiac tumors are true?


  1. Sarcomas are the most frequent primary malignancy.
  2. Metastatic tumors are usually asymptomatic.
  3. Adjuvant chemotherapy and irradiation are efficacious in prolonging survival.
  4. Intra-atrial extension of renal neoplasms is a contraindication for surgical resection.
  5. Constrictive physiology is an indication for operation.

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A. Sarcomas are the most frequent primary malignancy.

B. Metastatic tumors are usually asymptomatic.

DISCUSSION: Twenty per cent of primary cardiac tumors are some variant of sarcoma. Precise histologic classification is not imperative, as all have a similar clinical picture with rapid systemic dissemination and aggressive local invasion. In contrast, metastatic tumors cause symptoms in only 10% of patients. Unfortunately, most primary and secondary cardiac malignancies infrequently respond to systemic chemotherapy or mediastinal irradiation. Surgical treatment is most successful with renal tumors extending into the right atrium. Significant 5-year survival can be achieved with concomitant nephrectomy and intraatrial resection of the tumor thrombus. Relief of tamponade is worthwhile; however, extensive decortication provides little help.

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