Q:

The effect of high positive end-expiratory pressures (PEEP) on cardiac output is:

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The effect of high positive end-expiratory pressures (PEEP) on cardiac output is:


  1. None
  2. Increased cardiac output.
  3. Decreased cardiac output because of increased afterload to the left ventricle
  4. Decreased cardiac output because of decreased effective preload to the left ventricle.

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D. Decreased cardiac output because of decreased effective preload to the left ventricle.

DISCUSSION: Higher levels of PEEP can be associated with decreases in cardiac output as a consequence of an effective decrease in the preload to the left ventricle owing to impaired left ventricular filling. 

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