Multiple Endocrine Neoplasia (MEN) 2b is characterized by which of the following findings?
belongs to book: ASIR SURGICAL MCQs BANK|Dr. Gharama Al-Shehri|1st edition| Chapter number:9| Question number:57
All Answers
total answers (1)
belongs to book: ASIR SURGICAL MCQs BANK|Dr. Gharama Al-Shehri|1st edition| Chapter number:9| Question number:57
total answers (1)
a. Medullary carcinoma of the thyroid, pheochromocytoma, mucosal neuromas, and a distinctive marfanoid habitus
The multiple endocrine neoplasias are familial disorders typically characterized by predisposition to the development of tumors of multiple endocrine organs. These disorders are all inherited in an autosomal dominant fashion, and the tumors tend to be multicentric. The tumors may be benign or malignant and may occur metachronously or synchronously. MEN 1 is characterized by the concurrence of parathyroid hyperplasia, pancreatic islet cell tumors, and pituitary adenomas. MEN 2a consists of medullary carcinoma of the thyroid, pheochromocytoma, and parathyroid hyperplasia. MEN 2b includes medullary carcinoma of the thyroid, pheochromocytoma, mucosal neuromas, and a distinctive marfanoid habitus. Together, these syndromes encompass much of the spectrum of endocrine neoplasia.
need an explanation for this answer? contact us directly to get an explanation for this answer