Which of the following conditions are associated with hypercalcemia?

a. Hyperthyroidism

b. Thiazide diuretics 

d. Breast cancer

Multiple causes of hypercalcemia include the following: Malignancy

Vitamin A or D intoxication

Thiazide diuretics

Hyperthyroidism

Milk-alkali syndrome

Sarcoidosis and other granulomatous diseases

Familial hypocalciuric hypercalcemia

Immobilization

Paget’s disease

Lithium therapy

Addisonian crisis

Idiopathic hypercalcemia of infancy

Hyperthyroidism is associated with increased bone reabsorption. Often, the plasma PTH is low, and a history of other thyrotoxic symptoms can be elicited. Thiazides may increase serum calcium to a mild degree, primarily through hemoconcentration. Serum phosphate may also be depressed. It often takes several weeks for the hypercalcemia to resolve after the medication is discontinued. Terminal ileal resection is not associated with hypercalcemia, indeed hypocalcemia may develop with short gut syndrome. While ileal resection is a predisposing condition for the development of calcium oxalate kidney stones, this is the result of alterations in oxalate metabolism. Patients with solid tumors, such as lung carcinoma, breast carcinoma, squamous cell carcinoma of the head, neck, esophagus or female genital tract or renal cell cancer account for three quarters of all cases of humoral hypercalcemia of malignancy.