Q:

Secondary hyperparathyroidism:

waelhammad
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2022-12-09
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Secondary hyperparathyroidism:

  1. Is a metabolic disease in which the primary abnormality is decreased glomerular filtration rate.
  2. Is best treated initially by subtotal parathyroidectomy.
  3. Is caused by increased production of 1,25(OH) 2 vitamin D 3, causing increasing intestinal calcium absorption and hypercalcemia.
  4. Can have severe effects on bones exacerbated by aluminum contained in phosphate binders and dialysate water.
  5. Is best treated initially by total parathyroidectomy with autotransplantation.
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waelhammad
2022-12-09
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A. Is a metabolic disease in which the primary abnormality is decreased glomerular filtration rate.

D. Can have severe effects on bones exacerbated by aluminum contained in phosphate binders and dialysate water.

DISCUSSION: Secondary hyperparathyroidism is caused by renal disease, including decreased glomerular filtration rate and decreased 1,25(OH) 2 vitamin D 3 production. It is best treated by medical management restricting dietary phosphate, administering vitamin D and calcium with phosphate-binding gels, and limiting aluminum exposure, which can exacerbate bone disease.

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