Q:

The parathyroid glands:

waelhammad
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2022-12-09
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The parathyroid glands:

  1. Develop from the second and third pharyngeal pouches, along with the palatine tonsil and the thymus.
  2. Migrate caudally in the neck in normal development but can be found anywhere from the pharyngeal mucosa to the deep mediastinum
  3. Secrete PTH and calcitonin to manage calcium homeostasis.
  4. Usually number four, but frequently number only two or three
  5. Contain enzymes that catalyze the conversion of 25(OH) vitamin D 3 to 1,25(OH) 2 vitamin D 3.
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waelhammad
2022-12-09
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B. Migrate caudally in the neck in normal development but can be found anywhere from the pharyngeal mucosa to the deep mediastinum

DISCUSSION: The parathyroid glands develop from the third and fourth pharyngeal pouches, along with the thymus and the thyroid ultimobronchial body; there are four glands in the vast majority of persons. Calcitonin is secreted by the C cells of the thyroid. Vitamin D 3 hydroxylation occurs in the kidney. 

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