Q:

Which of the following forces do not promote the formation of interstitial fluid?

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Which of the following forces do not promote the formation of interstitial fluid?


  1. Increased venous pressure.
  2. Constrictive pericarditis.
  3. Hypernatremia.
  4. Hypoproteinemia

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C. Hypernatremia.

DISCUSSION: Interstitial fluid production is a function of the hydrostatic and colloid osmotic pressures across the capillary membrane. Forces tending to increase interstitial fluid flux across the capillary membrane include obstruction to outflow of the capillary due to structural or functional obstruction in the venous system or increase in venous pressure from any cause, reduction in osmotic pressure due to hypoproteinemia, and increase in pore size due to local mediators of inflammation.

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