The following statement(s) is/are true concerning the epidemiology of Crohn’s disease

d. First and second generation relatives with Crohn’s disease have an increased prevalence when compared to the general population

Crohn’s disease arises most commonly between the ages of 15 and 30 years, with a second peak at 55 to 60 years. Men and women are equally affected. The disease is seen more commonly in urban residents than rural dwellers and is associated with higher levels of education. The disease is almost exclusively encountered in industrialized nations like Western Europe and the United States which suggests that environmental factors are important in the pathogenesis. Aggregation in families can occur with first-and second-generation relatives of patients with Crohn’s disease found to have a 10-and 3-fold increase, respectively, in the prevalence of Crohn’s disease when compared to other non-related individuals.