Q:

Which of these statements about the digestion of fat are true?

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Which of these statements about the digestion of fat are true?


  1. Micellar solution provides an optimal environment for the action of pancreatic lipase
  2. Decreasing the pH below 5.5 increases the effectiveness of pancreatic lipase in hydrolyzing fat.
  3. Co-lipase blocks triglyceride hydrolysis.
  4. Lipase catalyzes the hydrolysis of dietary triglyceride into 2-monoglyceride and fatty acids.
  5. Fatty acids and 2-monoglyceride are held in micellar solutions.
  6. Fatty acid and 2-monoglyceride enter the intestinal cell by active transport.

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A. Micellar solution provides an optimal environment for the action of pancreatic lipase.

D. Lipase catalyzes the hydrolysis of dietary triglyceride into 2-monoglyceride and fatty acids

E. Fatty acids and 2-monoglyceride are held in micellar solutions.

DISCUSSION: Micellar solution provides an optimal environment for the action of pancreatic lipase. Pro-co-lipase is converted to co-lipase by trypsin. Co-lipase binds to triglyceride, then lipase complexes with co-lipase, and triglyceride hydrolysis access. Pancreatic lipase hydrolyzes triglyceride into 2-monoglyceride and fatty acids. The 2-monoglyceride and fatty acid enter the micellae. An alkaline pH allows lipase to function optimally. Micellar fatty acids and 2-monoglyceride pass into the epithelial cell by diffusion. 

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