Helicoabacter pylori has been investigated as a possible etiologic agent in duodenal ulceration. Which of the following statement(s) regarding H pylori infection in humans is/are correct?

b. H pylori possess cell surface receptors that bind to small intestinal mucous cells

c. Therapeutic regimens for duodenal ulcer that eliminate the organism are associated with lower ulcer recurrence rates than those in which the organism persists 

e. Antral gastritis is associated with development of duodenal ulcer 

Helicobacter pylori has received enormous investigative attention in recent years as a possible infectious cause of peptic ulceration. The evidence that H pylori causes ulcers is substantial but largely inferential. Antral gastritis is nearly always present in patients with duodenal ulceration. H pylori infestation of antral mucosa is believed to cause gastritis. While normal small intestinal cells do not permit H pylori binding, areas of gastric metaplasia are usually demonstrated in the duodenal mucosa immediately surrounding the ulcer. Resolution of gastritis follows eradication of the organism and drug regimens that are bactericidal are associated with lower rates of ulcer recurrence than those that have no anti-bacterial actions 

However, it is clear that not all patients infested with H pylori develop ulceration. Half of patients with dyspepsia but no ulceration have evidence of H pylori infestation and 20% of healthy volunteers can be demonstrated to harbor the organism. The incidence of infestation increases with age in the asymptomatic population.