Which of the following statements regarding intrinsic factor is/are correct?
belongs to book: ASIR SURGICAL MCQs BANK|Dr. Gharama Al-Shehri|1st edition| Chapter number:4| Question number:93
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belongs to book: ASIR SURGICAL MCQs BANK|Dr. Gharama Al-Shehri|1st edition| Chapter number:4| Question number:93
total answers (1)
c. Intrinsic factor secretion, like that of acid, is stimulated by gastrin, histamine, and acetylcholine
The gastric mucosa is the site of production of intrinsic factor, which is a necessary co-factor for the absorption of vitamin B12 by the ileal mucosa. Total gastrectomy and atrophic gastritis involving the proximal oxyntic mucosa are regularly followed by vitamin B12 deficiency, manifest as pernicious anemia. Acid-secreting parietal cells are the site of intrinsic factor synthesis. Like acid secretion, intrinsic factor secretion is stimulated by gastrin, histamine, and acetylcholine
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