Proteins that are destined to be secreted from the cells must pass through a series of organelles. These organelles include:

b. Golgi apparatus

d. Lysosomes 

Proteins targeted for the secretory pathway most commonly begin with translocation from the cytoplasm across the lipid bilayer into the lumen of the endoplasmic reticulum. It must then pass through a number of compartments including the Golgi apparatus where they are further processed and sorted and end up in a secretory vesicle or lysosome.