Q:

The evaluation of a patient scheduled for elective surgery should always include the following as tests of hemostasis and coagulation:

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The evaluation of a patient scheduled for elective surgery should always include the following as tests of hemostasis and coagulation:


  1. History and physical examination.
  2. Complete blood count (CBC), including platelet count.
  3. Prothrombin time (PT) and activated partial thromboplastin time (APTT).
  4. Studies of platelet aggregation with adenosine diphosphate (ADP) and epinephrine.

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A. History and physical examination.

DISCUSSION: The evaluation of most patients scheduled for elective surgery who do not have a history of significant bleeding disorders is somewhat controversial. An adequate history and physical examination screen out most patients with bleeding problems. For patients who are scheduled to undergo a major surgical procedure, it is advisable to obtain a CBC and platelet count, as well as a PT and APTT level. This detects a large number of bleeding disorders but does not rule out all possible causes of perioperative bleeding. Studies of platelet aggregation are indicated only for patients who are suspected of having qualitative defects of platelet function (e.g., von Willebrand's disease). 

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